Must-Read Books for Health Entrepreneurs: Wisdom, Strategy & Disruption

Looking to launch, scale, or sustain a health venture? Discover 15+ essential books every health entrepreneur must read—covering innovation, public health, funding, digital transformation, and African health systems. Curated for change-makers in healthcare.

Jun 23, 2025 - 03:42
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Must-Read Books for Health Entrepreneurs: Wisdom, Strategy & Disruption

"If you close your eyes to facts, you will learn through accidents." — African Proverb

Health entrepreneurship is not for the faint-hearted — especially in Africa where electricity might skip a town before your startup hits market fit. Whether you're building an AI-driven diagnostic app, a rural telemedicine platform, or a maternal health solution, you need wisdom beyond your WiFi.

Here’s a curated list of must-read books to help you build, lead, and sustain impactful health ventures. These books blend global expertise, African relevance, and timeless insight for entrepreneurs solving some of the world’s toughest health challenges.


1. The Innovator's PrescriptionClayton Christensen, Jerome Grossman & Jason Hwang

📚 Subtitle: A Disruptive Solution for Health Care
🔗 https://www.goodreads.com/book/show/5071152-the-innovator-s-prescription
🧠 Why Read It: A masterclass in disruptive innovation applied to healthcare. A must if you want to rethink systems, not just apps.


2. Start With WhySimon Sinek

🔗 https://simonsinek.com/product/start-with-why/
🔥 Why Read It: For health entrepreneurs chasing purpose, not just profit. Helps clarify your mission and communicate it.

"The one who asks questions doesn’t lose the way." — African Proverb


3. Lean Impact: How to Innovate for Radically Greater Social GoodAnn Mei Chang

🔗 https://leanimpact.org/book/
🌍 Why Read It: Tailored for social impact ventures — learn how to prototype, pivot, and deliver results in low-resource environments.


4. The Business of Health InnovationLawton R. Burns

🔗 https://www.cambridge.org/core/books/business-of-health-innovation/
📈 Why Read It: Explains the complex dance between pharma, payers, tech, and innovation. Useful for strategists and policy-minded founders.


5. How to Change the World: Social Entrepreneurs and the Power of New IdeasDavid Bornstein

🔗 https://www.goodreads.com/book/show/236982.How_to_Change_the_World
🌱 Why Read It: Real stories of innovators changing lives — from health to education. Inspiring and relatable.


6. Digital Doctor: Hope, Hype, and Harm at the Dawn of Medicine’s Computer AgeRobert Wachter

🔗 https://www.amazon.com/Digital-Doctor-Medicine-Computer-Age/dp/0071849468
💻 Why Read It: Helps you understand what goes right (and wrong) when medicine meets technology.


7. FactfulnessHans Rosling

🔗 https://www.gapminder.org/factfulness-book/
📊 Why Read It: A reality check for founders. Learn how the world — and health outcomes — are actually improving, despite media gloom.


8. The Mom TestRob Fitzpatrick

🔗 https://momtestbook.com/
🎯 Why Read It: Teaches you how to talk to users without leading them into flattery. Crucial for testing digital health ideas in the field.


9. Working in Public Health: A Canadian PerspectiveM. Elizabeth Thorpe

🔗 https://www.amazon.ca/Working-Public-Health-Elizabeth-Thorpe/dp/1551308394
📚 Why Read It: Gives practical insights into the multidisciplinary realities of public health work — useful even beyond Canada.


10. Good to GreatJim Collins

🔗 https://www.jimcollins.com/concepts/good-to-great.html
🏆 Why Read It: For HealthTech founders transitioning from MVP to scale. Focuses on team, discipline, and long-term greatness.


11. The Checklist ManifestoAtul Gawande

🔗 https://atulgawande.com/book/the-checklist-manifesto/
📋 Why Read It: Simple checklists save lives. Learn why even surgeons and pilots rely on them — and how you can use them in product design and operations.


12. African Health Leaders: Making Change and Claiming the FutureFrancis Omaswa & Nigel Crisp

🔗 https://global.oup.com/academic/product/african-health-leaders-9780198725045
🌍 Why Read It: Stories of African health system changemakers — from village nurses to national reformers. Rich in context, pride, and power.


13. Designing for Emerging Markets: How to Build Products for Africa & BeyondMelissa Huerta

🔗 https://www.melissahuerta.com/
💡 Why Read It: Understand user-centred design in underserved contexts — without assumptions or overdesign.


14. Venture DealsBrad Feld & Jason Mendelson

🔗 https://www.venturedeals.com/
💸 Why Read It: Demystifies term sheets and negotiations. Every health founder needs this before pitching VCs or donors.


15. Reimagining Global Health: An IntroductionPaul Farmer et al.

🔗 https://www.ucpress.edu/book/9780520271999/reimagining-global-health
🧬 Why Read It: Merges anthropology, ethics, and equity — a must-read for any health innovator working across cultures or continents.


Bonus Pick:

The Art of WarSun Tzu
🧠 Because sometimes... dealing with funders, regulators, or competitors feels like war.


Final Thoughts

Health entrepreneurship is a lonely path. Books are not just for knowledge — they are mentors in your backpack, guides in moments of doubt, and co-founders in spirit.

"Wisdom is like fire. People take it from others." — African Proverb

So light your fire. Build your library. And go disrupt, heal, and lead.

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editor-in-chief CTO/Founder, Doctors Explain Digital Health Co. LTD.. | Healthcare Innovator | Digital Health Entrepreneur | Editor-in-Chief MedClarity Journal | Educator| Mentor | Published Author & Researcher